It does not skip generations because the genetic errors may be present in any one of the 46 chromosomes that carry the genes, except for the sex chromosomes. Only one parent needs to transmit the abnormal gene, so the child has a 50% chance of inheriting the disorder.
Is muscular dystrophy always inherited?
In most cases, muscular dystrophy (MD) runs in families. It usually develops after inheriting a faulty gene from one or both parents. MD is caused by mutations (alterations) in the genes responsible for healthy muscle structure and function.
Can people with muscular dystrophy reproduce?
A man with Duchenne muscular dystrophy fathered two living children. He was 1 of 10 affected males in 5 generations. Clinical and genetic patterns, muscle biopsies, autopsy results, and serum enzymes were all compatible with the diagnosis of Duchenne muscular dystrophy.
Can people with muscular dystrophy have a baby?
Because of muscle weakness in areas that affect delivery-such as the abdomen, back, and uterus-women with muscular dystrophy may require a Caesarean section. For women whose muscular dystrophy affects their hearts, pregnancy is not advised.
Can you get muscular dystrophy later in life?
It can affect anyone from teenagers to adults in their 40s. Distal muscular dystrophy affects the muscles of the arms, legs, hands, and feet. It usually comes on later in life, between ages 40 and 60. Oculopharyngeal muscular dystrophy starts in a persons 40s or 50s.
Why do more boys get muscular dystrophy?
DMD generally affects boys because the dystrophin gene is on the X chromosome. Chromosomes are the parts of your cells that contain your genes. Boys only have one X chromosome. Girls have two X chromosomes, one from each parent.
How long does someone with DMD live?
Although there isnt a cure, the outlook for people with DMD is better than it has ever been. Years ago, children with the disease usually didnt live beyond their teens. Today, they live well into their 30s, and sometimes into their 40s and 50s.